Influence of intraperitoneal application of taurolidine on the perioperative metastases, tumor recurrence and survival rate after surgical resection of colorectal cancer

Study hypothesis: Recurrence rates after colon resection for cancer are 16% to 18% (Surgical Therapy Study Group). The study hypothesis is that the intraoperative intraperitoneal lavage with taurolidine reduces the 5-year recurrence rate from 16% to 10%. Primary outcome(s): Time to local and distant tumor relapse (disease free survival).