Data for: A Network Perspective on Comorbid Depression in Adolescents with Obsessive-compulsive Disorder

Participants The participants were 87 adolescents beginning treatment for OCD in the residential and intensive outpatient units of the Obsessive-Compulsive Disorder Center at Rogers Memorial Hospital. There were 41 (47.1%) males and 46 (52.9%) females, who ranged in age from 13 to 17 (M = 15.37, SD = 1.17). The racial/ethnic breakdown was Caucasian (n = 72), Asian (n = 10), Hispanic (n = 2), biracial (n = 2), and Black (n = 1). Board-certified staff psychiatrists, who are all experts in OCD and related disorders, used DSM-IV criteria to diagnose patients upon admission. These diagnoses were based on in-depth reviews of patients’ records from previous providers, information gathered by the hospital admissions staff, and an unstructured clinical interview with the adolescents and caretakers upon arrival at the treatment center. All participants received a primary diagnosis of OCD, and each consented for their data to be used in de-identified research. Current comorbid disorders according to these diagnoses were major depression (n = 21; 24.1%), depressive mood disorder not otherwise specified (n = 41; 47.1%, combined percentage = 71.3%), attention deficit hyperactivity disorder (n = 25; 28.7%), generalized anxiety disorder (n = 18; 20.7%), social anxiety disorder (n = 10; 11.5%), and tic/Tourette's syndrome (n = 8; 9.2%). Elevated comorbidities of current mood disorders is likely a result of the sample largely consisting of severe, clinically complex residential inpatients. Measures Children's Yale-Brown Obsessive Compulsive Scale Self-Report (CY-BOCS-SR; Scahill et al., 1997). The CY-BOCS-SR is a self-report questionnaire that evaluates the severity of OCD symptoms during the previous week. The scale includes 10 five-point Likert items which are summed to a score that ranges from 0-40 (a score of 16 or above signifies clinically significant severity). Reliability and validity of the self-report version of the scale are satisfactory (Scahill et al., 1997). The mean score in our sample was 26.1 (SD = 5.8, range = 24; Conelea, Schmidt, Leonard, Riemann, & Cahill, 2012). The 10 questions in the CY-BOCS-SR correspond to the 10 questions in the adult version of the scale (Y-BOCS; Goodman et al., 1989). Quick Inventory of Depressive Symptomatology (QIDS-SR; Rush et al., 2003). The QIDS-SR is a self-report questionnaire that evaluates the severity of depression symptoms. The scale includes 16 four-point Likert items summing to a total score ranging from 0-64. Reliability and validity of the scale are satisfactory (Rush et al., 2003). The mean score in our sample was 10.7 (SD = 5.9, range = 25).研究参与者 本研究的参与者为87名正在罗杰斯纪念医院强迫症中心（Obsessive-Compulsive Disorder Center at Rogers Memorial Hospital）的住院及强化门诊单元接受强迫症（Obsessive-Compulsive Disorder, OCD）治疗的青少年。其中男性41名，占比47.1%，女性46名，占比52.9%；年龄范围为13至17岁，平均年龄M=15.37，标准差SD=1.17。种族/族裔分布为白人72例、亚裔10例、西班牙裔2例、混血2例、黑人1例。所有经董事会认证的精神科医师均为强迫症及相关障碍领域的专家，他们采用DSM-IV诊断标准对入院患者进行诊断。诊断依据包括对既往诊疗机构提供的患者病历的详细审阅、医院入院工作人员收集的相关信息，以及患者与照料者抵达治疗中心后接受的非结构化临床访谈。所有参与者均被确诊为原发性强迫症，并同意将其去标识化后的数据用于本研究。根据本次诊断，当前共病障碍包括：重性抑郁症21例（24.1%）、未特定的抑郁心境障碍41例（47.1%，两类心境障碍合并占比71.3%）、注意缺陷多动障碍25例（28.7%）、广泛性焦虑障碍18例（20.7%）、社交焦虑障碍10例（11.5%）以及抽动/抽动秽语综合征8例（9.2%）。当前心境障碍共病率偏高，这可能源于本样本以病情严重、临床特征复杂的住院患者为主。 测评工具 1. 儿童耶鲁-布朗强迫症量表自评版（Children’s Yale-Brown Obsessive Compulsive Scale Self-Report, CY-BOCS-SR; Scahill等，1997） CY-BOCS-SR是用于评估过去一周内强迫症症状严重程度的自评问卷。该量表包含10个5点李克特式条目，所有条目得分相加得到总分，总分范围为0至40分，其中16分及以上提示存在临床意义上的显著症状严重程度。该自评版本的信效度表现良好（Scahill等，1997）。本样本的平均得分为26.1（SD=5.8，得分跨度为24；Conelea、Schmidt、Leonard、Riemann及Cahill，2012）。CY-BOCS-SR的10个条目与成人版量表（耶鲁-布朗强迫症量表Y-BOCS; Goodman等，1989）的10个条目一一对应。 2. 抑郁症状快速自评量表（Quick Inventory of Depressive Symptomatology, QIDS-SR; Rush等，2003） QIDS-SR是用于评估抑郁症状严重程度的自评问卷。该量表包含16个4点李克特式条目，总分范围为0至64分。该量表的信效度表现良好（Rush等，2003）。本样本的平均得分为10.7（SD=5.9，得分跨度为25）。