N6-Methyladenosine modification of mRNA regulates the transition from 2D to 3D growth in the moss Physcomitrium patens

NIAID Data Ecosystem2026-05-01 收录

m6A甲基化调控

植物生长模式转变

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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE213348 数据链接链接失效反馈

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This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

创建时间：

2023-05-10

Mettl3/m6A promotes translation of pathogenic mRNAs to mediate cystogenesis in mouse models of ADPKD

m6A甲基化调控

多囊肾病囊肿形成

Purpose: Determine the differential m6A methylation pattern of Mettl3 between wildtype, Pkd1F/RC-KO and Pkd1F/RC-Mettl3-DKO mouse kidneys. Methods: m6A RNA IP using the Magna MeRIPâ¢ m6A Kit (EMD Mil

NIAID Data Ecosystem70

YTHDF2 mediates the mRNA degradation in prostate cancer in m6A-dependent way. YTHDF2 mediates the mRNA degradation in prostate cancer in m6A-dependent way

m6A甲基化调控

前列腺癌分子机制

As the crucial m6A reader, YTHDF2 usually degrades the target mRNAs by recognizing the m6A modified sites, consequently altering m6A levels of each mRNA. In this study, we used m6A MeRIP sequencing to

NIAID Data Ecosystem40

METTL14 / YTHDF1 mediates m6A modification of PTBP1 to regulate PDGF-BB-induced airway smooth muscle cell function

哮喘分子机制

m6A甲基化调控

Increased proliferation and migration of abnormal airway smooth muscle cells (ASMCs) are significantly associated with asthma. This study aimed to investigate the effects of methyltransferase-like 14

NIAID Data Ecosystem40

MeRIP, RIP and RNA Sequencing of the H1299 stable cell lines which the endogenous YTHDF2 was silenced by a short hairpin RNA targeting YTHDF2 3’UTR (shYTHDF2) and then re-expressed Flag-tagged YTHDF2-WT orYTHDF2-K571R

m6A甲基化调控

RNA结合蛋白SUMOylation

SUMOylation affects many aspects of target proteins such as activity, stability, localization and protein-protein interactions. We have found that SUMOylation of YTHDF2 increased its binding activity

NIAID Data Ecosystem60

The function of Wtap in N6-adenosine methylation of mRNAs controls T cell receptor signaling and survival of T cells [YTHDF2-iCLIP]

m6A甲基化调控

核受体信号转导

T cell antigen receptor (TCR) signaling controls the development, activation and survival of T cells by involving several layers and numerous mechanisms of gene regulation. N6-methyladenosine (m6A) is

NIAID Data Ecosystem40

N6-Methyladenosine modification of mRNA regulates the transition from 2D to 3D growth in the moss Physcomitrium patens

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