Gene expression profile for male SD rats treated with high fat diet (HFD) and DNA methyltransferase (DNMT) inhibitor 5-aza-2′-deoxycytidine (5-AzaD) by RNA-Seq

To investigate the effects of HFD on affecting the gene expressions, as well as the methylation inhibitor 5-AzaD reversing such effects in the frontal cortex of male SD rats by RNA-Seq.本研究采用RNA测序（RNA-Seq）技术，探究高脂饮食（High Fat Diet, HFD）对雄性Sprague-Dawley（SD）大鼠前额叶皮层基因表达的影响，以及甲基化抑制剂5-AzaD对该效应的逆转作用。