No effect on blood leukocyte counts in LDLr KO mice receiving ORP8 KO bone marrow.

At 17 weeks after transplantation and after 9 weeks of WTD feeding, blood was isolated from bone marrow recipient animals. Blood leukocytes were counted using a hematology analyzer, and different subpopulations were quantified as percentage of total leukocytes. A) No difference between the ORP8 KO BM recipients and the wildtype (WT) BM recipients in the amount of circulating leukocytes. B–D) Similarly, there was no difference in the percentage of lymphocytes, neutrophils and monocytes of total leukocytes. N = 15, results are expressed as mean ±SEM and significance was assessed by Student T-test.