pvc in pregnancy

Objective: To investigate the outcomes of fetuses or neonates in pregnant women with premature ventricular contractions (PVCs). Methods: 6, 148 pregnant women were consecutively enrolled in the study. Of which, 103 women with premature ventricular contractions (PVCs) burden >0.5% were divided into two groups based on the presence or absence of adverse fetal or neonatal events. The adverse outcomes were compared between the groups to assess the impact of PVCs on pregnant. Results: A total of 19 adverse events (12 cases) occurred in 103 pregnant women with PVCs, which was significantly higher than those women without PVCs (11.65% vs. 2.93%, p<0.01). The median PVC burden in pregnant women with PVCs was 2.84% (1.02% to 6.1%). Furthermore, in comparison with the women without adverse events, the median PVCs burden was significantly higher in those women with adverse fetal or neonatal outcomes (9.02% vs. 2.30%, p<0.01). Multivariate logistic regression analysis demonstrated that the burden of PVCs was associated with the adverse fetal or neonatal outcomes in pregnant women with PVCs (OR:1.34, 95% CI (1.34-1.61), p<0.01). Conclusions: Frequent PVCs have adverse effects on pregnancy, and the PVCs burden might be an important factor associated with adverse fetal and neonatal outcomes in pregnant women with PVC. Our cohort of pregnant women study indicated that the higher burden of PVCs, the more likely the adverse events might occur.