Datasets for: Apoptosis and β-catenin inhibition in gastric cancer cells by chamomile extract

Description of the research dataset:This dataset contains the experimental data supporting the findings of the study titled " Overcoming Genetic Heterogeneity in Gastric Cancer: Chamomile Extract as a Dual Regulator of Mitochondrial Apoptosis and Wnt/β-Catenin Pathway in AGS and KATO III Cells". Background and Methodology:Gastric cancer remains a major cause of cancer-related mortality worldwide. To investigate safer therapeutic strategies, this study explored the anticancer activity of an aqueous extract of Matricaria chamomilla L. (chamomile) in AGS and KATO III human gastric adenocarcinoma cells. The dataset includes raw and processed data from key experiments: Cytotoxicity and Viability: Data from MTT assays quantifying the reduction in AGS and KATO III cells' viability after treatment with the chamomile extract. Apoptosis Induction: Flow cytometry data files (e.g., .fcs) and analysis results from Annexin V/Propidium iodide staining, demonstrating the pro-apoptotic effect. Phytochemical Analysis: Spectrophotometric data for total phenolic and flavonoid content, along with HPLC-DAD-ESI-MS/MS chromatograms and compound identification data used to characterize the individual phenolic constituents of the extract. These data provide the foundational evidence for the study's conclusions regarding the extract's induction of mitochondrial apoptosis and suppression of β-catenin signaling.