FT-ICR-MS based untargeted metabolomics for the discrimination of yeast mutants

The data consists of 3 replicates of 5 different strains of Saccharomyces cerevisiae: the reference BY4741 (or wild type) and 4 isogenic single-gene deletion mutants, ΔGLO1, ΔGLO2, ΔGRE3 (all related to methylglyoxal metabolism), and the control mutant ΔENO1. MS data were obtained from DI-ESI analysis in a 7T-Solarix XR FT-ICR-MS, operating in positive ionization mode. The raw data from the 15 samples were aligned using MetaboScape 4.0 (Brüker Daltonics) using the T-ReX algorithm. Normalization was performed using the standard leucine enkephalin.The files contain the data before normalization (5yeasts_notnorm.csv) and afternormalization by reference feature (5yeasts_norm.csv).