Pseudomonas aeruginosa is a high priority multi-drug-resistant (MDR) bacterial pathogen with increasing resistance against broad-spectrum antibiotics. Multiple efforts are ongoing to develop anti-pseu

NIAID Data Ecosystem00

Magnetic Separation and Antibiotics Selection Enable Enrichment of Cells with ZFN/TALEN-Induced Mutations

基因编辑技术

突变体筛选

The ability to enrich cells with targeted mutations greatly facilitates the process of using engineered nucleases, including zinc-finger nucleases and transcription activator-like effector nucleases,

Figshare2016-01-18 更新00

A screen for yeast mutants with defects in the dolichol-mediated pathway for N-glycosylation.

酵母信号通路

突变体筛选

Dolichol in the form of dolichyl phosphate participates in the synthesis of N- and O-linked glycoproteins and phosphatidylinositol-linked proteins in the yeast Saccharomyces cerevisiae. In this organi

PubMed Central1994-02-15 更新00

Template-Assisted De Novo Sequencing of SARS-CoV‑2 and Influenza Monoclonal Antibodies by Mass Spectrometry

抗体工程

病毒抗体结构

In this study, we used multiple enzyme digestions, coupled with higher-energy collisional dissociation (HCD) and electron-transfer/higher-energy collision dissociation (EThcD) fragmentation to develop

Figshare2022-06-02 更新00

ADAPT consensus Z-scores used in VHH-72 mutation selection.

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