首页/数据集/Type I Interferon Signaling via the EGR2 Transcriptional Regulator Potentiates CAR T cell-intrinsic Dysfunction

Type I Interferon Signaling via the EGR2 Transcriptional Regulator Potentiates CAR T cell-intrinsic Dysfunction

NIAID Data Ecosystem2026-03-14 收录

CART细胞功能障碍

免疫信号通路

数据链接：

https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE224194 数据链接链接失效反馈

官方服务：

资源简介：

This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

应用场景：

创建时间：

2023-02-21

相关数据集

Toll-like receptor signaling pathway

免疫信号通路

分子生物学

Specific families of pattern recognition receptors are responsible for detecting microbial pathogens and generating innate immune responses. Toll-like receptors (TLRs) are membrane-bound receptors ide

wikipathways.github.io220

Macrophages from Rosa26-integrated Cas9-expressing C57BL/6 mice have a putative TRIF-mediated defect in the TLR-3/4 signaling

免疫信号通路

基因编辑模型

In this study, we report that the TLR4 ligand, LPS, and TLR3 ligand polyinosinic:polycytidylic acid failed to activate IRF3 or STAT1 in bone marrowâderived macrophages (BMMs) isolated from two indep

NIAID Data Ecosystem60

IL-7 signaling pathway

免疫信号通路

细胞因子

Interleukin-7 (IL-7) was discovered in the year 1988 as a factor that enhanced the growth of murine B-cell precursors in bone marrow culture system. It was also known as lymphopoietin 1and pre-B cell

wikipathways.github.io50

Structure of human TSLP:TSLPR in complex with mouse IL-7Ralpha

蛋白质结构解析

免疫信号通路

Structure of human TSLP:TSLPR in complex with mouse IL-7Ralpha Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Cytokine receptor-like factor 2, Interleukin-7 receptor subunit alpha, ... Authors:

Protein Data Bank Japan2024-11-13 更新70

GO:0002753 (cytoplasmic pattern recognition receptor signaling pathway)

免疫信号通路

生物网络构建

This network was assembled automatically by INDRA (http://indra.bio) by processing all available biomedical literature with multiple machine reading systems, and integrating curated pathway databases.

NIAID Data Ecosystem60