The Microbial Protein Interaction Database

as stated 2017-06-09 MPIDB is no longer available under URL http://www.jcvi.org/mpidb/about.php The microbial protein interaction database (MPIDB) aims to collect and provide all known physical microbial interactions. Currently, 24,295 experimentally determined interactions among proteins of 250 bacterial species/strains can be browsed and downloaded. These microbial interactions have been manually curated from the literature or imported from other databases (IntAct, DIP, BIND, MINT) and are linked to 26,578 experimental evidences (PubMed ID, PSI-MI methods). In contrast to these databases, interactions in MPIDB are further supported by 68,346 additional evidences based on interaction conservation, protein complex membership, and 3D domain contacts (iPfam, 3did). We do not include (spoke/matrix) binary interactions infered from pull-down experiments.

据2017年6月9日所述，MPIDB数据库已不再可通过http://www.jcvi.org/mpidb/about.php的URL访问。微生物蛋白质相互作用数据库（MPIDB）旨在收集并提供所有已知的微生物物理相互作用信息。目前，该数据库中收录了250种细菌物种/菌株的蛋白质之间的24,295个实验确定的相互作用，用户可进行浏览和下载。这些微生物相互作用均经过人工从文献中整理或从其他数据库（如IntAct、DIP、BIND、MINT）导入，并与26,578个实验证据（PubMed ID、PSI-MI方法）相链接。与这些数据库不同，MPIDB中的相互作用还得到了68,346个额外证据的支持，这些证据基于相互作用保守性、蛋白质复合物成员资格和三维结构域接触（iPfam、3did）。我们不包含从捕获实验中推断出的（轮辐/矩阵）二元相互作用。