Fitness effects of de novo SNVs.

Columns give the SNV mutation type (nonsynonymous, conserved noncoding, or noncoding considering various percentages of noncoding sites under selection), mean selection coefficient for each category based on Torgerson et al. 2009 for noncoding mutations and Kim et al. 2017 for nonsynonymous mutations, mutation rate, target size (bp), expected number of mutations per genome (2*target size*mutation rate), and expected burden of new mutations (2*s*expected number of new mutations). (XLSX)