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Saccharomyces cerevisiae CYP51 (Lanosterol 14-alpha demethylase) G73E mutant complexed with itraconazole

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抗真菌药物

抗生素耐药性结构

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Saccharomyces cerevisiae CYP51 (Lanosterol 14-alpha demethylase) G73E mutant complexed with itraconazole

应用场景：

创建时间：

2023-09-27

基因组测序

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Whole genome sequencing of a clinical isolate of Trichophyton rubrum, carried out on Illumina platform with paired end reads. Samples relate to study investigating drug response of dermatophytes to an

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Crystal structure of Cryptococcus neoformans H99 Acetyl-CoA Synthetase in complex with Ac-AMS

蛋白质晶体

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Crystal structure of Cryptococcus neoformans H99 Acetyl-CoA Synthetase in complex with Ac-AMS

NIAID Data Ecosystem50

Transcriptional profiling of Aspergillus fumigatus H515 strain in response to alkaline or calcium shift. Aspergillus fumigatus

病原微生物应激响应

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The functional coupling of calcium-mediated signalling and alkaline tolerance has been demonstrated in multiple fungi. The applied relevance of such interplay extends most notably to fungal pathogens

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Minimal Inhibitory Concentration (MIC) of coumarin glycones and aglycones against fungi isolated from human superficial mycoses.

抗真菌药物

天然产物药效评估

All results are presented as the median MIC values from at least triplicate experiments with triplicate samples within each experiment. In all cases, the standard deviation was within 10% of the mean.

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Candida albicans dihydrofolate reductase complexed with NADPH and 5-[3-(2,5-dimethoxy-4-phenylphenyl)but-1-yn-1-yl]-6-methylpyrimidine-2,4-diamine (UCP111E)

抗真菌药物

抑制剂设计

Candida albicans dihydrofolate reductase complexed with NADPH and 5-[3-(2,5-dimethoxy-4-phenylphenyl)but-1-yn-1-yl]-6-methylpyrimidine-2,4-diamine (UCP111E) Descriptor: 5-[3-(2,5-dimethoxy-4-phenylphe

Protein Data Bank Japan2023-09-20 更新40

Saccharomyces cerevisiae CYP51 (Lanosterol 14-alpha demethylase) G73E mutant complexed with itraconazole

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