Cu(OAc)2/TFA-Promoted Formal [3 + 3] Cycloaddition/Oxidation of Enamines and Enones for Synthesis of Multisubstituted Aromatic Amines
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New strategies for the oxidative cycloaddition of enones with enamines are developed. These cycloaddition reactions directly afford substituted aromatic amines, which are important in organic chemistry, in moderate to good yield. Cu(OAc)2/TFA is shown to be essential to achieve high reaction efficiency.
创建时间:
2016-02-20



