Kinetics of ERK1/2, p38, RAC1 and RAS activation in LNCaP cells following cross-linking of anti-PSMA, anti-VCAM-1 or 7E11c mAba).

a)The 7E11c mAb recognizes an intracellular PSMA epitope and is therefore used as a further control of the experiment described.b)Results of gel densitometry are expressed as the ratio±SEM of activated/total protein as evaluated by measuring the respective areas.c)Statistical significance is reported with respect to the “No treatment” data.d)ns = not significant.e)nd = not determined.