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Circadian Cryptochrome 1 (CRY1) Rhythmically Modulates the DNA Damage Response

NIAID Data Ecosystem2026-03-12 收录

昼夜节律调控

DNA损伤修复

数据链接：

https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE144962 数据链接链接失效反馈

官方服务：

资源简介：

This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

应用场景：

创建时间：

2021-01-27

DNA损伤修复

抗癌药物设计

Homologous recombination repair (HRR), a crucial approach in DNA damage repair, is an attractive target in cancer therapy and drug design. The Bloom syndrome protein (BLM) is a 3′–5′ DNA helicase that

NIAID Data Ecosystem40

Circadian ribosome profiling reveals a role for the Period2 upstream opening reading frame in sleep

昼夜节律调控

睡眠神经机制

Many mammalian proteins have circadian cycles of production and degradation, but de novo transcription is only responsible for a small fraction of this rhythmicity. We used ribosome profiling to quant

NIAID Data Ecosystem00

Circadian Cryptochrome 1 (CRY1) Rhythmically Modulates the DNA Damage Response [ChIP-seq]

前列腺癌DNA损伤修复

昼夜节律调控

These studies identify a novel node of AR-regulated DNA repair through CRY1 directly regulating HR-mediated DNA repair to enhance cancer progression and discern a potential avenue to be targeted in la

NIAID Data Ecosystem00

WRNIP1 is recruited to DNA interstrand crosslinks and promotes repair

DNA损伤修复

DNA相互作用

Mass spectrometry data relating to Figure 1 and Table S1.

NIAID Data Ecosystem40

Dpo4 extension ternary complex with 3'-terminal primer G base opposite the 1-methylguanine (M1G) lesion

DNA损伤修复

结构生物学

Dpo4 extension ternary complex with 3'-terminal primer G base opposite the 1-methylguanine (M1G) lesion

NIAID Data Ecosystem00