HDMX (14-111; C17S) COMPLEXED WITH COMPOUND 13 AT 2.1A; Structural states of Hdm2 and HdmX: X-ray elucidation of adaptations and binding interactions for different chemical compound classes

HDMX (14-111; C17S) COMPLEXED WITH COMPOUND 13 AT 2.1A; Structural states of Hdm2 and HdmX: X-ray elucidation of adaptations and binding interactions for different chemical compound classes Descriptor: 1,4,7,10,13,16-HEXAOXACYCLOOCTADECANE, 6-chloranyl-3-[3-[(1~{S})-1-(4-chlorophenyl)ethyl]-5-phenyl-imidazol-4-yl]-~{N}-[2-(4-cyclohexylpiperazin-1-yl)ethyl]-1~{H}-indole-2-carboxamide, GLYCEROL, ... Authors: Kallen, J. Deposit date: 2018-12-18 Release date: 2019-05-15 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Structural States of Hdm2 and HdmX: X-ray Elucidation of Adaptations and Binding Interactions for Different Chemical Compound Classes. Chemmedchem, 14, 2019

HDMX（14-111；C17S）与化合物13结合形成的复合物，衍射分辨率为2.1埃；人双微体2（Hdm2）与人双微体X（HdmX）的结构状态：X射线解析不同化学化合物类别的适配特征与结合相互作用。描述符：1,4,7,10,13,16-六氧杂环十八烷、6-氯-3-[3-[(1S)-1-(4-氯苯基)乙基]-5-苯基-咪唑-4-基]-N-[2-(4-环己基哌嗪-1-基)乙基]-1H-吲哚-2-甲酰胺、甘油等。作者：Kallen, J.。存放日期：2018-12-18。发布日期：2019-05-15。最后修改日期：2024-01-24。实验方法：X射线衍射（2.1 Å）。引用文献：《Structural States of Hdm2 and HdmX: X-ray Elucidation of Adaptations and Binding Interactions for Different Chemical Compound Classes》，Chemmedchem，14卷，2019年