Human TPC2 in Complex with Antagonist (S)-SG-094
收藏Protein Data Bank Japan2025-07-02 更新2026-06-30 收录
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https://pdbj.org/mine/summary/8ouo
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Human TPC2 in Complex with Antagonist (S)-SG-094 Descriptor: (1S)-6-methoxy-2-methyl-7-phenoxy-1-[(4-phenoxyphenyl)methyl]-3,4-dihydro-1H-isoquinoline, 1,2-DIACYL-SN-GLYCERO-3-PHOSHOCHOLINE, 2-{[(4-O-alpha-D-glucopyranosyl-alpha-D-glucopyranosyl)oxy]methyl}-4-{[(3beta,9beta,14beta,17beta,25R)-spirost-5-en-3-yl]oxy}butyl 4-O-alpha-D-glucopyranosyl-alpha-D-glucopyranoside, ... Authors: Chi, G, Pike, A.C.W, Maclean, E.M, Li, H, Mukhopadhyay, S.M.M, Bohstedt, T, Wang, D, McKinley, G, Fernandez-Cid, A, Duerr, K. Deposit date: 2023-04-24 Release date: 2024-06-12 Last modified: 2025-07-02 Method: ELECTRON MICROSCOPY (3 Å) Cite: Structural basis for inhibition of the lysosomal two-pore channel TPC2 by a small molecule antagonist. Structure, 32, 2024
创建时间：
2023-04-24
