GPCRs of unknown structure that were used in the analysis.

NIAID Data Ecosystem2026-03-06 收录

偶联受体药理

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https://figshare.com/articles/dataset/_GPCRs_of_unknown_structure_that_were_used_in_the_analysis_/554339 数据链接链接失效反馈

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GPCRs of unknown structure that were used in the analysis.

创建时间：

2009-09-16

Molecular insights into mechanisms of GPCR hijacking by Staphylococcus aureus

神经毒素-受体相互作用

偶联受体药理

We use hydrogen-deuterium exchange mass spectrometry (HDX-MS) to analyse the effects of S. aureus leucotoxins binding to the atypical chemokine receptor ACKR1 on receptor's structure and dynamics.

NIAID Data Ecosystem50

Table_4_Phylum-Spanning Neuropeptide GPCR Identification and Prioritization: Shaping Drug Target Discovery Pipelines for Nematode Parasite Control.xlsx

寄生虫药物靶点发现

偶联受体药理

Nematode parasites undermine human health and global food security. The frontline anthelmintic portfolio used to treat parasitic nematodes is threatened by the escalation of anthelmintic resistance, r

NIAID Data Ecosystem40

GPCR Trajectory files with modulators

偶联受体药理

分子药物设计

G-protein-coupled receptors (GPCRs) make up the largest superfamily of human membrane proteins and represent primary targets of ∼1/3 of currently marketed drugs. Allosteric modulators have emerged as

Figshare2024-11-01 更新30

Table_2_GPCRomics of Homeostatic and Disease-Associated Human Microglia.xlsx

偶联受体药理

神经退行性分子机制

G-protein-coupled receptors (GPCRs) are critical sensors affecting the state of eukaryotic cells. To get systematic insight into the GPCRome of microglia, we analyzed publicly available RNA-sequencing

NIAID Data Ecosystem40

Receptor quaternary organization explains G protein-coupled receptor family structure.. Homo sapiens

GPCR四级结构

偶联受体药理

Purpose: To investigate the quaternary structures of Rhodopsin-family GPCRs. Method: Analyzed 60 receptors from HEK 293T cells. Results: 1) Most of these receptors are monomers. 2) The phylogenetic di

NIAID Data Ecosystem40

GPCRs of unknown structure that were used in the analysis.

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