Asymmetric Approach to Hyacinthacines B1 and B2
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Naturally occurring hyacinthacines B1 and B2 have been prepared from a common, easily available, advanced intermediate. The approach features several highly stereoselective transformations: inter alia, a dichloroketene–enol ether [2 + 2] cycloaddition, a Bruylants alkylation, and an amino-nitrile alkylation–reduction.
创建时间:
2016-02-19



