Bi(OTf)3‑Catalyzed Diastereoselective One-Pot Synthesis of 1,3-Diamines with Three Continuous Stereogenic Centers
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A highly modular, diastereoselective one-pot-synthesis of 1,3-diamines with three contiguous stereogenic centers is reported. Our method provides a fast and efficient access to 1,2-anti-2,3-anti-1,3-diamines from three readily available building blocks. This Bi(OTf)3-catalyzed reaction is insensitive to air and moisture and can be performed on a multigram scale.
创建时间：
2018-09-20
