E-GEOD-59089

NIAID Data Ecosystem2026-05-02 收录

红系发育表观遗传调控

PRC2功能研究

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资源简介：

RNA-seq transcriptional profiling in primary human erythroid progenitor cells upon shRNA-mediated knockdown of PRC2 core subunits

创建时间：

2025-01-24

RNA-seq dataset for MPNST cell lines. RNA-seq dataset for MPNST cell lines

癌细胞转录组

PRC2功能研究

Comprehensive transcriptomic profiling of PRC2 mutant and WT MPNST cell lines were performed to investigate PRC2-dependent transcriptional programs that are activated due to PRC2 loss Overall design:

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Paramecium tetraurelia strain:51 Raw sequence reads. Paramecium tetraurelia strain:51

基因重组机制

PRC2功能研究

To reveal the mechanism of PRC2 in genome rearrangement of Paramecium tetraurelia

NIAID Data Ecosystem20

Polycomb PRC2 antagonizes de novo DNA methylation at the maternal Gtl2-Rian-Mirg locus [Affymetrix Expression]. Mus musculus

PRC2功能研究

甲基化调控基因

Wild-type mouse embryonic stem cells are compared with mutants for components of PRC2 including Ezh2-/-, Eed-/-, and Jarid2-/- cells. Gene expression microarrays were used to compare the expression fo

NIAID Data Ecosystem20

Genome-wide maps of the H3K27me3 histone modification in wild-type or SUZ12-mutant ipNF05.5 cells.

H3K27me3修饰分析

PRC2功能研究

Using ChIP-seq, we profiled the H3K27me3 histone mark in wild-type or SUZ12-mutant ipNF05.5 cells. Overall design: Examination of the H3K27me3 histone modification in wild-type or SUZ12-mutant ipNF05.

NIAID Data Ecosystem30

ChIP-seq in MEG3+ and MEG3- hIPSCs

PRC2功能研究

非编码RNAMEG3调控

In this experiment we sought to identify region with differential PRC2, JARID2, and H3K27me3 occupancy in human induced pluripotent stem cell lines with silenced or expressed MEG3 locus to indirectly

NIAID Data Ecosystem20

E-GEOD-59089

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