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Synthesis of 3,4-Disubstituted 2<i>H</i>-Benzopyrans through C−C Bond Formation via Electrophilic Cyclization

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NIAID Data Ecosystem2026-03-06 收录
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The electrophilic cyclization of substituted propargylic aryl ethers by I2, ICl, and PhSeBr produces 3,4-disubstituted 2H-benzopyrans in excellent yields. This methodology results in vinylic halides or selenides under mild reaction conditions and tolerates a variety of functional groups, including methoxy, alcohol, aldehyde, and nitro groups.

创建时间:
2016-02-29
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