Health aspects of geraniol
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Abstract Background: Geraniol (GE), as secondary metabolites of plant and natural bioactive essential oils is one of the major compounds of Rosa damascena Mill and widely used as fragrance/flavor in the food industry. Rosa damascena Mill and geraniol have numerous health benefits for human consumption. Currently, there is no single article that extensively covers the complete range of beneficial effects of GE that could improve knowledge in this category. Objective: The purpose of this study was to provide a comprehensive review of all published specific articles about beneficial properties of GE, as a monoterpene component of medicinal plants. Methods: Data were selected from Scopus, Clarivate Web Of ScienceTM, Embase, ScienceDirect and PubMed databases from 1940-2019 by identifying keywords and creating complex searches. Results: Based on the search results, GE identified as a natural compound having insecticidal and repellent activities. GE introduces a new class of cancer chemopreventive agents due to its citronellol and trans-geraniol. Other functional properties such as antibacterial, antifungal, antioxidant and anti-inflammatory of GE have also been found. Conclusion: Overall, this approach has been a systematic literature review to provide an effective strategy for rapidly evaluating research results. This study suggests that the GE and Rosa damascena Mill have multiple health benefits and they are recommended for their therapeutic effects. Keywords: Geraniol; Medicinal plant; Bioactivity; Rosa damascene
背景：香叶醇（Geraniol）作为植物次生代谢产物与天然活性精油成分，是大马士革玫瑰（Rosa damascena Mill）的主要活性成分之一，被广泛用作食品工业中的香精香料。大马士革玫瑰与香叶醇对人体具有诸多健康益处。目前尚无一篇文章全面涵盖香叶醇的全部有益功效，以助力该领域的知识积累。 目的：本研究旨在全面综述所有已发表的、关于香叶醇作为药用植物单萜成分的有益特性的专题文献。 方法：本研究检索了1940年至2019年间Scopus、科睿唯安Web of ScienceTM、Embase、ScienceDirect及PubMed数据库中的相关文献，通过确定关键词并构建复合检索式完成文献筛选。 结果：基于检索结果，香叶醇被证实为兼具杀虫与驱避活性的天然化合物。因其含有香茅醇与反式香叶醇，香叶醇可作为一类新型癌症化学预防剂。此外，研究还发现香叶醇具备抗菌、抗真菌、抗氧化及抗炎等多种功能特性。 结论：总体而言，本研究采用系统文献综述方法，为快速评估研究成果提供了高效策略。本研究表明，香叶醇与大马士革玫瑰具备多重健康益处，其治疗价值值得推广应用。 关键词：香叶醇；药用植物；生物活性；大马士革玫瑰
