Mitochondrial import efficiency of ATFS-1 regulates mitochondrial UPR activation.

Alliance of Genome Resources2026-08-01 收录

未折叠蛋白反应

ATFS-1输入效率调控

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Mitochondrial import efficiency of ATFS-1 regulates mitochondrial UPR activation.

ATFS-1的线粒体导入效率调控线粒体未折叠蛋白反应（mitochondrial UPR）的激活

Effect of neuron-specific spliced XBP1 (XBP1s) overexpression on gene expression in the mouse brain. Effect of neuron-specific spliced XBP1 (XBP1s) overexpression on gene expression in the mouse brain

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One major component of cellular proteome resides in the endoplasmic reticulum (ER), the key organelle for protein biogenesis in the secretory pathway. Disruption of ER proteostasis leads to ER stress,

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Genes with ATF5 binding sites within their promoters from Uncovering a mitochondrial unfolded protein response in corals and its role in adapting to a changing world

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结肠干细胞

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The effect of ER-stress and subsequent activation of the unfolded protein response was investigated in colon cancer stem cells and more differentiated colon cancer cells Human colon cancer derived sph

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Additional file 5: of Combined flow cytometry and high-throughput image analysis for the study of essential genes in Caenorhabditis elegans

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Raw data of Phsp-6::GFP reporter measurements. Gene-by-gene data of the fold change (FC) and adjusted P value (adj.pvalue) obtained after data analysis. RNAi clones appear ordered by their position in

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The unfolded protein response supports cellular robustness as a broad-spectrum compensatory pathway.

未折叠蛋白反应

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Stress pathways monitor intracellular systems and deploy a range of regulatory mechanisms in response to stress. One of the best-characterized pathways, the unfolded protein response (UPR), is respons

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Mitochondrial import efficiency of ATFS-1 regulates mitochondrial UPR activation.

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