Structure of human soluble guanylate cyclase in the cinciguat-bound activated state
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Structure of human soluble guanylate cyclase in the cinciguat-bound activated state Descriptor: 4-({(4-carboxybutyl)[2-(2-{[4-(2-phenylethyl)benzyl]oxy}phenyl)ethyl]amino}methyl)benzoic acid, Guanylate cyclase soluble subunit alpha-1, Guanylate cyclase soluble subunit beta-1, ... Authors: Chen, L, Liu, R, Kang, Y. Deposit date: 2020-10-14 Release date: 2021-08-11 Last modified: 2024-05-29 Method: ELECTRON MICROSCOPY (3.8 Å) Cite: Activation mechanism of human soluble guanylate cyclase by stimulators and activators. Nat Commun, 12, 2021
人可溶性鸟苷酸环化酶(soluble guanylate cyclase)结合西尼胍(cinciguat)的激活态结构
描述物:4-({(4-羧基丁基)[2-(2-{[4-(2-苯乙基)苄基]氧基}苯基)乙基]氨基}甲基)苯甲酸、可溶性鸟苷酸环化酶可溶性亚基α1、可溶性鸟苷酸环化酶可溶性亚基β-1……
作者:Chen L、Liu R、Kang Y
提交日期:2020-10-14
发布日期:2021-08-11
最后更新:2024-05-29
研究方法:电子显微镜(分辨率3.8埃)
引用文献:刺激剂与激活剂介导的人可溶性鸟苷酸环化酶激活机制。《自然·通讯》,12卷,2021年
创建时间:
2020-10-14



