Source data: Olive leaf extract ameliorates hyperglycaemia, oxidative stress, and pancreatic and hepatic injury in streptozotocin-induced diabetic rats (animal-level dataset, n = 48)

Animal-level source data for the study "Olive Leaf Extract Ameliorates Hyperglycaemia, Oxidative Stress, and Pancreatic and Hepatic Injury in Streptozotocin-Induced Diabetic Rats: A Dose-Dependent Comparison with Metformin." Forty-eight male Wistar rats were randomised to six groups (n = 8): Normal, Normal + olive leaf extract (OLE) 400 mg/kg, Diabetic, Diabetic + OLE 200 mg/kg, Diabetic + OLE 400 mg/kg, and Diabetic + metformin 200 mg/kg. The workbook contains per-animal fasting blood glucose, HbA1c, serum insulin, HOMA-IR and HOMA-beta, OGTT time-course and AUC, separate pancreatic and hepatic oxidative-stress markers (MDA, GSH, SOD, CAT), semi-quantitative histopathology scores, hepatic congestion-area morphometry, omnibus ANOVA and post-hoc results, a statistical annex, the HPLC method, reagent and kit details, and a methods-values sheet. Version 3 provides independently scored pancreatic and hepatic histopathology (correcting an earlier version in which liver injury scores duplicated the pancreatic scores in several groups); the summary medians/IQR and Kruskal-Wallis statistics (pancreas H = 42.49, liver H = 39.64) were updated accordingly. Provided to support the corresponding manuscript submitted to FARMACIA (Romanian Society of Pharmaceutical Sciences). Licensed CC BY 4.0.