NGS data related to Adam et al.: On the accuracy of the epigenetic copy machi...

B2FIND2026-03-19 收录

表观遗传复制准确性

DNMT1功能研究

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https://b2find.eudat.eu/dataset/79aa3196-f950-5a05-9cb5-3705c129f5ef 数据链接链接失效反馈

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资源简介：

Expression and purification of DNMT1 for biochemical work Full length murine DNMT1 (UniProtKB P13864) was overexpressed and purified as described (Adam, et al. 2020) using the...

RNA sequencing identifies differentially expressed genes in embryonic cardiomyocytes following knockdown of DNMT1 expression for 72 h. Mus musculus

心肌细胞基因表达

DNMT1功能研究

Purpose: This study aims to identify the differentially expressed genes in embryonic cardiomyocytes following the knockdown of DNMT1 expression. Methods: Primary cardiomyocytes were isolated from mous

NIAID Data Ecosystem90

Rescuing DNMT1 Fails to Fully Reverse the Molecular and Functional Repercussions of Its Loss in Mouse Embryonic Stem Cells [mRNA-seq]

DNMT1功能研究

胚胎表观遗传调控

Epigenetic mechanisms are crucial for developmental programming and can be disrupted by environmental stressors, increasing susceptibility to disease. This has sparked interest in therapies for restor

NIAID Data Ecosystem00

DNA methylation, through DNMT1, has an essential role in the development of gastrointestinal smooth muscle cells and disease [RNA-Seq]

胃肠道平滑肌细胞发育

DNMT1功能研究

DNA methylation is a key epigenetic modification that can regulate gene expression. Genomic DNA hypomethylation is commonly found in many gastrointestinal (GI) diseases. Dysregulated gene expression i

NIAID Data Ecosystem00

Gene expression of the Dnmt1/3a/3b TKO ESCs which ubiquitously express full-length DNMT1(TKO_FL) or a deletion mutant DNMT1 lacking the N-terminal 602 amino acids(TKO_602).

胚胎干细胞分化

DNMT1功能研究

Gene expression analysis of TKO_FL ESCs and TKO_602 ESCs(day 0), differentiated cells from each ESCs(day4 and day7). To form embryoid bodies (EBs), all ES cells were cultured in MEF medium without LIF

NIAID Data Ecosystem30

Rescuing DNMT1 Fails to Fully Reverse the Molecular and Functional Repercussions of Its Loss in Mouse Embryonic Stem Cells [EM-seq]

DNMT1功能研究

胚胎干细胞表观遗传学

NIAID Data Ecosystem00