Fully Orthogonally Protected 2-Deoxystreptamine from Kanamycin
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A fully orthogonally protected and enantiopure 2-deoxystreptamine derivative is prepared in a few straightforward steps from commercially available kanamycin. Resolution of a sterically hindered diacetate was effected by a Verenium esterase and was followed by a chemoselective Staudinger reduction−acylation protocol.
创建时间：
2008-07-04
