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资源简介：
This SuperSeries is composed of the SubSeries listed below. Overall design: Refer to individual Series
应用场景：
创建时间：
2012-07-16
相关数据集
Genetic_screens_in_haploid_ES_cells___. Genetic_screens_in_haploid_ES_cells___
The project involves the genetic screens in haploid mouse ES cells. Genetic screens in mouse ES cells were budgeted as part of the 5 year plan, but the sequencing money was swept up and consolidated w
NIAID Data Ecosystem60
G2/M transition for stabilizing mouse haploid ESCs: Gene Expression
To compare the gene expression profiles between haploid ESCs and diploid ESCs, we examined the gene expression profile using DNA microarray analysis using G1 phase cells collected by FACS. Two indepen
NIAID Data Ecosystem50
Derivation and differentiation of haploid human embryonic stem cells [SNP array]
Diploidy is a fundamental genetic feature in mammals, in which haploid cells normally arise only as post-meiotic germ cells that serve to insure a diploid genome upon fertilization. Gamete manipulatio
NIAID Data Ecosystem40
A genetic screen identifies Etl4-deficiency capable of stabilizing the haploidy in embryonic stem cells
We performed a genome-wild loss-of-function screening and revealed several gene mutations could significantly reduce the rate of self-diploidization in haESCs. We further demonstrated that CRISPR/Cas9
NIAID Data Ecosystem60
Reduced diploidization and survival improvement of semi-cloned mice produced from androgenetic haploid embryonic stem cells. Mus musculus
We found that the overall DNA methylation and hydroxymethylation in AG-haESCs are extremely low, and the downregulation of both de novo methyltransferase Dnmt3b and methylation maintenance enzyme Dnmt
NIAID Data Ecosystem50
