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CD73-Dependent Adenosine Signaling through Adora2b Drives Immunosuppression in Ductal Pancreatic Cancer

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NIAID Data Ecosystem2026-05-01 收录
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In this experiment, we evaluted whole transcriptomic changes in ex vivo cultured ducts expressing mutant Kras compared to control ducts. The cells were cultured for 7 days before RNA was isolated for RNA-seq. Overall design: For the ex vivo cultured ducts, Hnf1b:CreERT2; LSL-KrasG12V mice were given 10 mg tamoxifen or corn oil control and euthanized at day 4 for ex vivo culturing of ducts.

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2023-07-25
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