The abundance of deleterious polymorphisms in humans
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http://datadryad.org/dataset/doi%253A10.5061%252Fdryad.br63t4d0
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Here I show a gradual decline in the proportion of deleterious nonsynonymous SNPs (nSNPs) from tip to root of the human population tree. This study reveals that up to 48% of nSNPs specific to a single genome are deleterious in nature, which underscores the abundance of deleterious polymorphisms in humans.
创建时间：
2012-11-05
