Firstly, 27 orthogonal experiments were constructed with COMSOL 6.0 software, and TC1, TC2, and TC3 were extracted by Matlab 2022b software，seen in the "TC1, TC2, and TC3 of 27 orthogonal experiments.
(#)Ultrasonic irradiation time.(*)The Negative peak value of acoustic pressure measured by hydrophone in water.($)The time from injecting microbubbles into vessels to ultrasonic irradiation.
