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Division-Specific Accessibility Program of B cell Differentiation. Mus musculus
B cell differentiation occurs over multiple cellular divisions and involves a switch in transcriptional programs that allows for antibody secretion. The transcription factors that drive this process h
NIAID Data Ecosystem40
Role of SWI/SNF-Related, Matrix Associated, Actin Dependent Regulator of Chromatin A4 (SMARCA4) core complex in epithelial innate response (ATAC-seq). Role of SWI/SNF-Related, Matrix Associated, Actin Dependent Regulator of Chromatin A4 (SMARCA4) core complex in epithelial innate response (ATAC-seq)
We examine the epigenetic role of the SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin A4 (SMARCA4) in the epithelial response to RSV infection. Wild type and SMARCA4 silence
NIAID Data Ecosystem30
Studying changes in chromatin accessibility in A549 cells by ATAC-seq directly after 4-hour glucocorticoid treatment and following a 24-hour hormone washout
We performed ATAC-seq in the A549 cell line. Cells were treated with dexamethasone (100 nM), hydrocortisone (100 nM) or vehicle (ethanol) for 4 hours and either harvested immediately or washed 2x with
NIAID Data Ecosystem30
Tousled-like kinase activity is required for transcriptional silencing and suppression of innate immune signaling [HeLa ATAC-Seq]
The Tousled like kinases 1 and 2 (TLK1/2) control histone deposition through the ASF1 histone chaperones and are regulated by the DNA damage response. Depletion of TLK activity caused replication stre
NIAID Data Ecosystem40
Summary of features of TAMC and existing footprinting tools for ATAC-seq data.
Summary of features of TAMC and existing footprinting tools for ATAC-seq data.
Figshare2022-09-12 更新30
