Statistics of the disruption styles.

The genes of high abundance are described in Table 1, and those of low abundance are referred to as homologs with a normalized percentage <0, as shown in Fig. 5a. The ORFs and Blast results of the reads for these genes are summarized. The average length of the metareads and the longest ORFs identified within them were first measured for each gene and then used to obtain the average for the 701 genes. On the basis of the Blast results, five scenarios of the matches to known genes were defined: complete, disrupted, transverse, shift, and unknown. ROB1 and ROB2 for a further evaluation of the size of the ORFs were measured (see Materials and Methods).