Transcriptional Regulation by the Alcoholic Extract of Polygala arvensis Willd. in the Mouse Nucleus Accumbens

to explore the underlying mechanisms of PAW-mediated effects on neural plasticity, a discovery strategy based on high-throughput transcriptome sequencing was applied. The NAc was harvested from mice received four days of a range of doses of PAW treatment (0, 8, 16, and 32 g/kg) for sequencing. Each sample was prepared by combining the tissue from two mice within the same treatment group.