Photocatalytic Three-Component Reaction for the Synthesis of Multifunctional Diaryl Sulfides

A photocatalytic
three-component reaction of a nitroarene, a thiophenol,
and a ketone for the synthesis of multifunctional diaryl sulfides
was reported using a nitro group as the nitrogen source and thiophenol
as the sulfur source. Thiophenol also serves as a proton donor to
reduce nitroarene to arylamine as a key intermediate for the formation
of C–N and C–S bonds. Good functional group tolerance
and mild reaction conditions make this method have practical synthetic
value for diversified multifunctional diaryl sulfides.