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Enantioselective Synthesis of Hemiaminals via Pd-Catalyzed C–N Coupling with Chiral Bisphosphine Mono-oxides

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NIAID Data Ecosystem2026-03-09 收录
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https://figshare.com/articles/dataset/Enantioselective_Synthesis_of_Hemiaminals_via_Pd_Catalyzed_C_N_Coupling_with_Chiral_Bisphosphine_Mono_oxides/2113918
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资源简介:
A novel approach to hemiaminal synthesis via palladium-catalyzed C–N coupling with chiral bisphosphine mono-oxides is described. This efficient new method exhibits a broad scope, provides a highly efficient synthesis of HCV drug candidate elbasvir, and has been applied to the synthesis of chiral N,N-acetals.
创建时间:
2016-02-12
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