Plasma concentrations of angiogenic factors (VEGF, TIMP-1), insulin and glucose¹.

1Two-way ANOVA and Tukey contrasts were performed to compare differences among the groups of LLC-bearing mice; a priori contrasts were performed to compare differences in AIN93G-fed wild-type mice with or without LLC (control vs. AIN WT). Values (means ± SEM) in a row with different superscripts are significantly different at p≤0.05 for LLC-bearing groups (n = 10 per group). *p<0.01 compared to AIN WT. Control: AIN93G-fed non-tumor-bearing wild-type mice, AIN WT: AIN93G-fed wild-type mice, AIN PAI-1−/−: AIN93G-fed PAI-1−/− mice, HF WT: high-fat fed wild-type mice, HF PAI-1−/−: high-fat fed PAI-1−/− mice, D × G: diet × gene interaction. Plasma concentrations of angiogenic factors (VEGF, TIMP-1), insulin and glucose1.