An Unusual Intramolecular Hetero-Diels−Alder Cycloaddition
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https://figshare.com/articles/dataset/An_Unusual_Intramolecular_Hetero_Diels_Alder_Cycloaddition/3291109
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资源简介：
A new reaction of erythronolides, an intramolecular hetero-Diels−Alder, has been discovered. Heated aqueous alcoholic
solutions of ABT-773 (1) and its cis isomer (3) convert slowly
to cycloadducts 2 and 4, respectively. Optimal reaction
conditions, mechanistic studies supported by molecular
modeling, and biological activity data are reported. Single-crystal X-ray structures for both adducts 2 and 4 have been
obtained.
创建时间：
2016-05-06
