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Respiratory chain function, measured as oxygen consumption (O<sub>2</sub> flux/pmol/(s x mg), mean±SEM) with high resolution respirometry on isolated liver mitochondria using SUIT protocol [19] with sequential addition of substrates, ADP, and inhibitors, showed significant changes in sick 27–29 day

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*FCCP, Carbonyl cyanide-4-(trifluoromethoxy)phenylhydrazone, uncoupler showing maximal capacity. **TMPD N,N,N′,N′-tetramethyl-p-phenylenediamine.

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2014-01-22
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