Effects of Doxycycline, Esomeprazole, Lidocaine, Rapamycin, Glibenclamide, Ketamine, Tris Buffer and Their Combinations on Anaplastic Thyroid Cancer Cells: A dataset on the anticancer effects of drugs and their combinations

The raw data were submitted as supplementary file with the article. The file has five dataset of absorbance reading of the wells in 96 plate and cell viablilty rate caculated for each drug or drug combination. These data were analysed and the analysed data were presented in tables and figures. In figure 1, The inhibition rate of Esomeprazole, Lidocaine, Rapamycin, Glibenclamide and Ketamine was compared to that of their combinations. In figure 2, The inhibition rate of Esomeprazole, Glibenclamide and Doxycycline was compared to that of their combinations. In figure 3, The inhibition rate of Doxycycline, Rapamycin, Ketamine and Tris Buffer was compared to that of their combinations. The inhibition rate of each drug and their combination was presented in table 1. For identifying synergistic drug combinations, Q value was calculated for each drug combination using Jin's formula and was demonsterated in table 2.本研究的原始数据随论文一并作为补充材料提交。该补充文件包含5组数据集，分别为96孔板内各孔的吸光度读数，以及每种药物或药物联合处理后的细胞存活率计算结果。上述原始数据已完成分析，分析结果以表格与图示形式呈现。 图1对比了埃索美拉唑（Esomeprazole）、利多卡因（Lidocaine）、雷帕霉素（Rapamycin）、格列本脲（Glibenclamide）与氯胺酮（Ketamine）的单药抑制率及其联合用药抑制率。 图2对比了埃索美拉唑、格列本脲与多西环素（Doxycycline）的单药抑制率及其联合用药抑制率。 图3对比了多西环素、雷帕霉素、氯胺酮与Tris缓冲液（Tris Buffer）的单药抑制率及其联合用药抑制率。 表1汇总了所有单药及其联合用药的抑制率数据。为筛选具有协同作用的药物联合方案，本研究采用金氏公式（Jin's formula）计算了每种药物联合的Q值（Q value），相关结果汇总于表2。