Effects of rescue analgesia with transversus abdominis plane block on pain and oxygenantion after abdominal surgery: a randomized controlled trial

Abdominal surgery is a common surgical procedure that is frequently associated with substantial postoperative pain. However, rescue analgesia using opioids is associated with several adverse effects. The transversus abdominis plane block (TAPB) has been demonstrated to be effective as part of multimodal analgesia. This study aimed to evaluate the effects of rescue analgesia using TAPB after abdominal surgery. Our data revealed that rescue analgesia with TAPB on the first postoperative day provided significantly greater pain relief for patients undergoing abdominal surgery than opioids. Furthermore, TAPB helped improve oxygenation, sleep quality, and reduced the degree of postoperative nausea and vomiting. However, we observed no inter-group differences in postoperative opioid consumption, gastrointestinal function, or quality of life.腹部手术是一类常见外科术式，术后往往伴随程度较重的疼痛。然而，采用阿片类药物实施补救性镇痛常伴随多种不良反应。腹横肌平面阻滞（transversus abdominis plane block, TAPB）已被证实作为多模式镇痛方案的组成部分具有良好疗效。本研究旨在评估腹部手术后采用TAPB实施补救性镇痛的效果。本研究数据显示，术后首日采用TAPB实施补救性镇痛，对腹部手术患者的镇痛效果显著优于阿片类药物。此外，TAPB可改善患者氧合状态与睡眠质量，并减轻术后恶心呕吐程度。但本研究未观察到两组患者在术后阿片类药物消耗量、胃肠道功能及生活质量方面存在显著差异。