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Targeting Transcriptional Addictions in Small Cell Lung Cancer with a Covalent CDK7 Inhibitor (Affymetrix)

ChEBI2014-10-23 更新2026-07-21 收录

细胞癌靶向治疗

转录调控药物研究

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-62609 数据链接链接失效反馈

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资源简介：

Targeting Transcriptional Addictions in Small Cell Lung Cancer with a Covalent CDK7 Inhibitor (Affymetrix)

应用场景：

创建时间：

2014-10-23

药物递送系统

细胞癌靶向治疗

Galactose-modified selenium nanoparticles (GA-SeNPs) loading with doxorubicin (DOX) for hepatocellular carcinoma (HCC) therapy was investigated in this paper. Selenium nanoparticles (SeNPs) were modif

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Activation of the PI3K/mTOR Pathway following PARP Inhibition in Small Cell Lung Cancer

细胞癌靶向治疗

PARP-PI3K/mTOR通路机制

Small cell lung cancer (SCLC) is an aggressive malignancy with limited treatment options. We previously found that PARP is overexpressed in SCLC and that targeting PARP reduces cell line and tumor gro

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DataSheet1_Discovery of a New CDK4/6 and PI3K/AKT Multiple Kinase Inhibitor Aminoquinol for the Treatment of Hepatocellular Carcinoma.ZIP

细胞癌靶向治疗

激酶抑制剂药物发现

Background: Hepatocellular carcinoma (HCC) is a lethal malignancy lacking effective treatment. The Cyclin-dependent kinases 4/6 (CDK4/6) and PI3K/AKT signal pathways play pivotal roles in carcinogenes

NIAID Data Ecosystem20

Suppression of AKT Anti-Apoptotic Signaling by a Novel Drug Candidate Results in Growth Arrest and Apoptosis of Hepatocellular Carcinoma Cells

细胞癌靶向治疗

AKT信号通路

Hepatocellular carcinoma (HCC) is the third most common cause of cancer fatalities worldwide, with limited treatment options and five year survival rates of between <5 and 15%. To address this medical

NIAID Data Ecosystem30

Nanocarrier-based delivery of arsenic trioxide for hepatocellular carcinoma therapy - Supplementary dataset

纳米药物递送

细胞癌靶向治疗

Hepatocellular carcinoma (HCC) poses a severe threat to human health and economic development. Despite many attempts at HCC treatment, most are inevitably affected by the genetic instability and varia

Figshare2023-02-15 更新30

Targeting Transcriptional Addictions in Small Cell Lung Cancer with a Covalent CDK7 Inhibitor (Affymetrix)

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