Lesion characteristics and mutation spectrum.

KCNJ5 mutation spectrum and prevalence. Significant overrepresentation of female patients with a lesion harboring KCNJ5 mutation, both adenomas and adenomas with associated hyperplasia. Males with adenomas harboring KCNJ5 mutations were significantly younger at the time of surgery and these adenomas were significantly larger than those without mutation. †, ‡, ¶ and #indicate p-value<0.005.