TCR affinity-dependent functional inhibition via PD-1 and SHP-1 phosphatase

ChEBI2013-02-11 更新2026-07-21 收录

细胞信号传导

免疫检查点调控

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-42922 数据链接链接失效反馈

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资源简介：

TCR affinity-dependent functional inhibition via PD-1 and SHP-1 phosphatase

创建时间：

2013-02-11

寻找Celastrol诱导AR和GR降解相关的蛋白质机器的数据集

细胞信号传导

蛋白质相互作用

"该数据集主要为了寻找参与调控AR和GR稳定性的关键成员。利用外界刺激处理前列腺癌细胞系，使得 AR 和 GR 处于不同的稳态，进而通过免疫共沉淀-质谱鉴定的方式，比较不同外界刺激下 AR 或 GR 结合的蛋白质机器差异，获得通过相互作用直接调控 AR 或 GR 稳态的蛋白质机器组分。数据量11 MB"

国家基础学科公共科学数据中心150

Type III interferon signaling

细胞信号传导

免疫学

The recently identified type III interferon group consists of three IFN-λ (lambda) genes encoding molecules called IFN-λ1, IFN-λ2 and IFN-λ3 (also called IL29, IL28A and IL28B respectively). These IFN

wikipathways.github.io90

PDPK1 phosphorylates AKT at T308

细胞信号传导

磷酸化蛋白质

Once AKT is localized at the plasma membrane, it is phosphorylated at two critical residues for its full activation. These residues are a threonine (T308 in AKT1) in the activation loop within the cat

reactome.org40

DLL3 binds NOTCH1

蛋白质相互作用

细胞信号传导

DLL3 interacts with NOTCH1 when the two proteins are expressed in the same cell (inferred from mouse homologs). The interaction occurs in endosomes and targets NOTCH1 for degradation in lysosomes befo

reactome.org100

The retinal pigment epithelium displays electrical excitability and lateral signal spreading: dataset

视网膜电生理

细胞信号传导

This is a dataset to the manuscript "The retinal pigment epithelium displays electrical excitability and lateral signal spreading" by Irina Ignatova, Roman Frolov and Soile Nymark

NIAID Data Ecosystem50

TCR affinity-dependent functional inhibition via PD-1 and SHP-1 phosphatase

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