Septic cardiomyopathy is the main complication and cause of death of severe sepsis with limited therapeutic strategy. However, the molecular mechanism of sepsis-induced cardiac injury remains unclear.

NIAID Data Ecosystem30

Data_Sheet_2_Prevalence of Phosphatidylinositol-3-Kinase (PI3K) Pathway Alterations and Co-alteration of Other Molecular Markers in Breast Cancer.docx

乳腺癌分子分型

PI3K信号通路

Background: PI3K/AKT signaling pathway is activated in breast cancer and associated with cell survival. We explored the prevalence of PI3K pathway alterations and co-expression with other markers in b

NIAID Data Ecosystem10

Phosphoproteomic analysis of signaling downstream of p85β

磷酸化蛋白质组学

PI3K信号通路

p85β is a regulatory subunit of phosphatidylinositol 3-kinase. The signaling mechanism of p85β is poorly understood. Quantitative mass spectrometry-based phosphoproteomic analysis was therefore perfor

NIAID Data Ecosystem40

The Human Adenovirus E4-ORF1 Protein Subverts Discs Large 1 to Mediate Membrane Recruitment and Dysregulation of Phosphatidylinositol 3-Kinase

病毒-宿主相互作用

PI3K信号通路

Adenoviruses infect epithelial cells lining mucous membranes to cause acute diseases in people. They are also utilized as vectors for vaccination and for gene and cancer therapy, as well as tools to d

NIAID Data Ecosystem10

Additional file 10: of CDC42 controls the activation of primordial follicles by regulating PI3K signaling in mouse oocytes

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