Introduction: Nonsteroidal anti-inflammatory drug (NSAID)-induced small intestinal damage is a serious and escalating clinical problem without effective treatment. Lafutidine (LAF) is a novel histamin
We examined the effects of the PDE9 inhibitor BAY 73-6691 on the kidney and heart for the first time in a 5/6 nephrectomy animal model using BAY 73-6691 dosages known to be effective in other rat dise