RNA-seq of small intestinal organoids treated with an inhibitor for the epigenetic modifier LSD1. RNA-seq of small intestinal organoids treated with an inhibitor for the epigenetic modifier LSD1
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To assess the role of LSD1 in mice small intestinal epithelium, small intestinal organoids were treated with an inhibitor for LSD1 (GSK-LSD1) and compared to untreated organoids. Similar to intestinal epithelium from mice with an intestinal epithelium specific LSD1-KO, paneth cells dissappear upon GSK-LSD1 treatment. We used these sequencing data to show that these small intestinal organoids have a similar phenotype as mice epithelium without LSD1.
创建时间:
2020-11-17



