Nx animals that showed a loss in aversive-related memory and attention were included in the CI group (Nx-CI) (n = 14) and compared to animals with intact learning (Nx-M n = 12 and Sham n = 20 groups).
Interventions: A: Placebo. Patients in this group receive placebo for 3 years with adjuvant chemotherapy(mFOLFOX6, CAPOX ,or capecitabine). B: Aspirin. Patients in this group receive aspirin, at a do
Interventions: Aspirin (100 mg/day) enteric-coated tablet Placebo tablet / day Primary outcome(s): Only the occurrence of a colorectal tumor (adenoma or cancer) is selected as the primary endpoint. S